Endocrine Abstracts

Introduction: Some studies suggest that thyroid autoimmunity might be associated with increased cardiovascular-risk. However, the exact pathophysiology of this relationship has not yet been fully understood. In this study we aimed to analyze the influence of the levothyroixine (L-T4) replacement therapy and of anti-thyroperoxidase antibodies (TPOAbs) on homocysteine (Hcy) levels in patients with thyroid autoimmune disease.Method...

Introduction: Vitamin D is postulated to play a significant role in the immune system modulation and its deficiency has been reported in some autoimmune disorders. Polymorphisms of different vitamin D-related genes, among them vitamin D receptor gene (VDR), could either be a risk factor for autoimmune diseases. Therefore the aim of the study was to assess the association between VDR Cdx2 (rs11568820) polymorphism and autoimmune thyroid disease (AITD) among th...